![]() It is recommended that clinical practice decisions are based on evidence emanating from well-conducted RCTs when available 1. IntroductionĮvidence from randomized controlled trials (RCTs) is considered to be at the top of the evidence pyramid. This manuscript provides a step-by-step guide to planning, conducting, analyzing and reporting RCTs. In this review, we provide simple descriptive guidance on planning, conducting, analyzing and reporting randomized controlled trials.Īppropriately planned and rigorously conducted randomized controlled trials (RCTs) remain the most robust research method available to find the real effect of an intervention, but a biased RCT can lead to the adoption of a wasteful intervention and may even harm patients. However, designing and conducting an randomized controlled trial, analyzing data, interpreting findings and disseminating results can be challenging as there are several practicalities to be considered. Therefore, randomized controlled trials are becoming increasingly popular in all areas of clinical medicine including perinatology. Evidence-based clinical practice improves patient outcomes and safety, and is generally cost-effective. ![]() Furthermore, randomized controlled trials yield themselves well to systematic review and meta-analysis providing a solid base for synthesizing evidence generated by such studies. High-quality evidence can be generated by performing an randomized controlled trial when evaluating the effectiveness and safety of an intervention. ![]() The randomized controlled trial is the most rigorous and robust research method of determining whether a cause–effect relation exists between an intervention and an outcome. ![]() A randomized controlled trial is a prospective, comparative, quantitative study/experiment performed under controlled conditions with random allocation of interventions to comparison groups. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |